Representative Papers
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Concomitant suppression of TH2 and TH17 cell responses in allergic asthma by targeting retinoic acid receptor-related orphan receptor γt.
Na H, Lim H, Choi G, Kim BK, Kim SH, Chang YS, Nurieva R, Dong C, Chang SH, Chung Y. J Allergy Clin Immunol. 2018 Jun;141(6):2061-2073.e5. -
Fibrinogen cleavage products and Toll-like receptor 4 promote the generation of programmed cell death 1 ligand 2-positive dendritic cells in allergic asthma.
Cho M, Lee JE, Lim H, Shin HW, Khalmuratova R, Choi G, Kim HS, Choi WS, Park YJ, Shim I, Kim BS, Kang CY, Kim JO, Tanaka S, Kubo M, Tung HY, Landers CT, Corry DB, Kheradmand F, Chung Y. J Allergy Clin Immunol. 2018 Aug;142(2):530-541. -
Atherogenic dyslipidemia promotes autoimmune follicular helper T cell responses via IL-27.
Ryu H, Lim H, Choi G, Park YJ, Cho M, Na H, Ahn CW, Kim YC, Kim WU, Lee SH, Chung Y. Nat Immunol. 2018 Jun;19(6):583-593. -
IL-27 confers a protumorigenic activity of regulatory T cells via CD39.
Park YJ, Ryu H, Choi G, Kim BS, Hwang ES, Kim HS, Chung Y. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3106-3111. -
Defining the role of transforming growth factor β1 in Foxp3+ T regulatory cells.
Choi G, Kim BS, Chang JH, Chung Y. Immunity. 2021 Mar 9;54(3):393-394. -
Type 17 immunity promotes the exhaustion of CD8+ T cells in cancer.
Kim BS, Kuen DS, Koh CH, Kim HD, Chang SH, Kim S, Jeon YK, Park YJ, Choi G, Kim J, Kang KW, Kim HY, Kang SJ, Hwang S, Shin EC, Kang CY, Dong C, Chung Y. J Immunother Cancer. 2021 Jun;9(6):e002603. -
Critical regulation of follicular helper T cell differentiation and function by Gα13 signaling.
Kuen DS, Park M, Ryu H, Choi G, Moon YH, Kim JO, Kang KW, Kim SG, Chung Y. Proc Natl Acad Sci U S A. 2021 Oct 26;118(43):e2108376118. -
Nanovesicle-Mediated Targeted Delivery of Immune Checkpoint Blockades to Potentiate Therapeutic Efficacy and Prevent Side Effects.
Jung M, Kang M, Kim BS, Hong J, Kim C, Koh CH, Choi G, Chung Y, Kim BS. Adv Mater. 2022 Mar;34(9):e2106516. -
Liver X receptor controls follicular helper T cell differentiation via repression of TCF-1.
Kim J, Lee H, Lee JE, Choi G, Chung H, Kim D, Park MJ, Gye YS, Shin KS, Kang CY, Kwok SK, Chung Y. Proc Natl Acad Sci U S A. 2023 Feb 28;120(9):e2213793120. -
A Personalized Cancer Vaccine that Induces Synergistic Innate and Adaptive Immune Responses.
Kuen DS, Hong J, Lee S, Koh CH, Kwak M, Kim BS, Jung M, Kim YJ, Cho BS, Kim BS, Chung Y. Adv Mater. 2023 Sep;35(36):e2303080. -
A Personalized Cancer Nanovaccine that Enhances T-Cell Responses and Efficacy Through Dual Interactions with Dendritic Cells and T Cells.
Go S, Jung M, Lee S, Moon S, Hong J, Kim C, Chung Y, Kim BS. Adv Mater. 2023 Dec;35(49):e2303979. -
Tonic type 2 immunity is a critical tissue checkpoint controlling autoimmunity in the skin.
Lee JE, Kim M, Ochiai S, Kim SH, Yeo H, Bok J, Kim J, Park M, Kim D, Lamiable O, Lee M, Kim MJ, Kim HY, Ronchese F, Kwon SW, Lee H, Kim TG, Chung Y. Cell Rep. 2024 Jul 23;43(7):114364. -
NRF2 is a spatiotemporal metabolic hub essential for the polyfunctionality of Th2 cells.
Choi G, Ju HY, Bok J, Choi J, Shin JW, Oh H, Jeon Y, Kim J, Kim D, Moon H, Lee JE, Keum YS, Kim YM, Kim HY, Park SH, Han MR, Chung Y. Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2319994121.